The First Spouse Gold Coin program arranged for the issuance of a design featuring Liberty as originally presented on a United States coin in circulation during that President's era. In the case of Thomas Jefferson’s term as President, the program chose a representation of Liberty as she appeared on Chief Mint Engraver Robert Scot's Draped Bust Half-Cent coin design, which had been in production between the years of 1800–1808.

The coin's reverse features an image of Jefferson's Burial Monument located at his estate in Monticello, as sculpted by Mint designer/engraver Charles Vickers. The coin also references Jefferson's self-written epitaph, noting many of his most famous accomplishments.

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